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Evidence is primarily derived from small clinical and preclinical studies
However, synthetic antioxidants are cost-efficient, have a wide availability, and provide stability advantages over natural antioxidants, 22 but have been associated with some deleterious side effects in human cells giving rise to controlled usage/consumption
Given that Gq is a key player in the amplification of GSIS, particularly under diabetic conditions, these findings highlight a GLP-1 receptor-centric pharmacological profile that underlies the potent effects of this multi-receptor agonist
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